Treatment results of 71 patients, operated because of craniopharyngiomas, at whom 95 operations were performed, that has made 1,3 surgical interventions per one patient, were analyzed. Age of patients was from 2 to 63 years. Conducting clinical syndromes depending on age, sizes and an anatomic variant of tumor growth were selected and clinical features of disease were determined. While quality of life estimation according to Karnofsky Scale it was revealed that at punction method application the quality of life after operation increased on 9,6 points, but further decreased on 7 points because of often relapses and necessity of repeated operations performing. At endoscopic method application quality of life after operation increased on 15 points and on 14,1 points more in remote terms. At microsurgical removal of a tumor quality of life after operation increased on 6,7 points and on 10,9 points more — in remote terms. On the basis of obtained data analysis the algorithm for surgical treatment of patients with craniopharyngiomas was developed.