
We introduce a simulation-based, amortised Bayesian inference scheme to infer the parameters of random walks. Our approach learns the posterior distribution of the walks' parameters with a likelihood-free method. In the first step a graph neural network is trained on simulated data to learn optimized low-dimensional summary statistics of the random walk. In the second step an invertible neural network generates the posterior distribution of the parameters from the learnt summary statistics using variational inference. We apply our method to infer the parameters of the fractional Brownian motion model from single trajectories. The computational complexity of the amortized inference procedure scales linearly with trajectory length, and its precision scales similarly to the Cram{é}r-Rao bound over a wide range of lengths. The approach is robust to positional noise, and generalizes well to trajectories longer than those seen during training. Finally, we adapt this scheme to show that a finite decorrelation time in the environment can furthermore be inferred from individual trajectories.
FOS: Computer and information sciences, Computer Science - Machine Learning, [SDV.BIBS] Life Sciences [q-bio]/Quantitative Methods [q-bio.QM], [PHYS.PHYS.PHYS-BIO-PH] Physics [physics]/Physics [physics]/Biological Physics [physics.bio-ph], FOS: Physical sciences, [INFO.INFO-LG] Computer Science [cs]/Machine Learning [cs.LG], Quantitative Biology - Quantitative Methods, Machine Learning (cs.LG), Biological Physics (physics.bio-ph), Physics - Data Analysis, Statistics and Probability, FOS: Biological sciences, Physics - Biological Physics, [PHYS.PHYS.PHYS-DATA-AN] Physics [physics]/Physics [physics]/Data Analysis, Statistics and Probability [physics.data-an], Data Analysis, Statistics and Probability (physics.data-an), Quantitative Methods (q-bio.QM)
FOS: Computer and information sciences, Computer Science - Machine Learning, [SDV.BIBS] Life Sciences [q-bio]/Quantitative Methods [q-bio.QM], [PHYS.PHYS.PHYS-BIO-PH] Physics [physics]/Physics [physics]/Biological Physics [physics.bio-ph], FOS: Physical sciences, [INFO.INFO-LG] Computer Science [cs]/Machine Learning [cs.LG], Quantitative Biology - Quantitative Methods, Machine Learning (cs.LG), Biological Physics (physics.bio-ph), Physics - Data Analysis, Statistics and Probability, FOS: Biological sciences, Physics - Biological Physics, [PHYS.PHYS.PHYS-DATA-AN] Physics [physics]/Physics [physics]/Data Analysis, Statistics and Probability [physics.data-an], Data Analysis, Statistics and Probability (physics.data-an), Quantitative Methods (q-bio.QM)
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