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Epilepsy & Behavior
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Increasing volume and complexity of pediatric epilepsy surgery with stable seizure outcome between 2008 and 2014: A nationwide multicenter study

A nationwide multicenter study
Authors: Barba C; Specchio N; Guerrini R; TASSI, LORENZO; De Masi S; Cardinale F; PELLACANI, SIMONA; +20 Authors

Increasing volume and complexity of pediatric epilepsy surgery with stable seizure outcome between 2008 and 2014: A nationwide multicenter study

Abstract

The objective of the study was to assess common practice in pediatric epilepsy surgery in Italy between 2008 and 2014.A survey was conducted among nine Italian epilepsy surgery centers to collect information on presurgical and postsurgical evaluation protocols, volumes and types of surgical interventions, and etiologies and seizure outcomes in pediatric epilepsy surgery between 2008 and 2014.Retrospective data on 527 surgical procedures were collected. The most frequent surgical approaches were temporal lobe resections and disconnections (133, 25.2%) and extratemporal lesionectomies (128, 24.3%); the most frequent etiologies were FCD II (107, 20.3%) and glioneuronal tumors (105, 19.9%). Volumes of surgeries increased over time independently from the age at surgery and the epilepsy surgery center. Engel class I was achieved in 73.6% of patients (range: 54.8 to 91.7%), with no significant changes between 2008 and 2014. Univariate analyses showed a decrease in the proportion of temporal resections and tumors and an increase in the proportion of FCDII, while multivariate analyses revealed an increase in the proportion of extratemporal surgeries over time. A higher proportion of temporal surgeries and tumors and a lower proportion of extratemporal and multilobar surgeries and of FCD were observed in low (<50surgeries/year) versus high-volume centers. There was a high variability across centers concerning pre- and postsurgical evaluation protocols, depending on local expertise and facilities.This survey reveals an increase in volume and complexity of pediatric epilepsy surgery in Italy between 2008 and 2014, associated with a stable seizure outcome.

Keywords

Male, Adolescent, Surgical approach, Seizures/etiology, Practice Patterns, Epilepsy surgery, Seizures, Physicians'/trends, Humans, Epilepsy/etiology, Practice Patterns, Physicians', Preschool, Survey, Child, Children, Epilepsy surgery Evaluation protocol Surgical approach Survey, Retrospective Studies, Epilepsy, Temporal Lobe/surgery, Infant, Practice Patterns, Physicians'/trends, Temporal Lobe, Children; Epilepsy surgery; Evaluation protocol; Surgical approach; Survey; Neurology; Neurology (clinical); Behavioral Neuroscience, Treatment Outcome, Italy, Child, Preschool, Health Care Surveys, Female, Evaluation protocol, Follow-Up Studies

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    popularity
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    influence
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selected citations
These citations are derived from selected sources.
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
31
Top 10%
Top 10%
Top 10%
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