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Impact of inner hydrophobicity of dendrimer nanomicelles on biodistribution: a PET imaging study

Authors: Roussel, Tom; Cruz-Dubois, Twiany; Louis, Beatrice; Laurini, Erik; Ding, Ling; Balasse, Laure; Nail, Vincent; +6 Authors

Impact of inner hydrophobicity of dendrimer nanomicelles on biodistribution: a PET imaging study

Abstract

This study reports the impact of increased hydrophobicity of the amphiphilic dendrimer on hydrophilic/hydrophobic balance and consequently on the self-assembly and subsequent biodistribution.

Keywords

hydrophilic-hydrophobic balance, [SDV.IB.IMA]Life Sciences [q-bio]/Bioengineering/Imaging, [SDV]Life Sciences [q-bio], [SDV.CAN]Life Sciences [q-bio]/Cancer, dendrimer, [SDV.CAN] Life Sciences [q-bio]/Cancer, Amphiphilic dendrimer, 616, bioimaging, biodistribution, [CHIM.ORGA]Chemical Sciences/Organic chemistry, molecular modeling, nanomicelle, 500, self-assembly, ITC, 540, [CHIM.ORGA] Chemical Sciences/Organic chemistry, self-assembling, [SDV] Life Sciences [q-bio], [SDV.IB.IMA] Life Sciences [q-bio]/Bioengineering/Imaging, dendrimer; nanomicelles; ITC; molecular modeling; self-assembly

  • BIP!
    Impact byBIP!
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    These citations are derived from selected sources.
    This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
    0
    popularity
    This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
    Average
    influence
    This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
    Average
    impulse
    This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
    Average
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selected citations
These citations are derived from selected sources.
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
0
Average
Average
Average
Green
hybrid