The aim of the work was obtaining a stable suspension based on biocompatible substances with application of biogenic metal nanoparticles encapsulated into NaCl salt matrix, as a precursor. Water-soluble complex based on different amine derivatives with antiseptic properties was selected as a liquid for salt dissolution. The solution was subjected to dispersion using ultrasonication at elevated temperature. Dispersion is accompanied by salt shell removal with simultaneous formation of an organic shell on the surfaces of metal nanoparticles that ensure their stabilization. Study of the suspension after soaking at room temperature for 100 days showed that its characteristics remain stable. A method for producing a stable colloidal solution based on nanoparticles of biogenic metal (Cu, Co, fem etc.) was developed. Metal nanopowder encapsulated into salt shell was used as a precursor. It is shown that such colloidal solutions are characterized by narrow size dispersion, as well as stability to temperature impact and time factor.