
Type A insulin resistance (IR) syndrome is a very uncommon genetic disorder affecting the insulin receptor (INSR) gene, characterized by severe IR without the presence of obesity. Patients with this condition will eventually develop diabetes, presenting a variable response to insulin-sensitizers, such as metformin and thiazolidinediones, and high doses of insulin. We report for the first time the results of the use of combination therapy with a glucagon-like peptide-1 receptor agonist and a sodium-glucose cotransporter 2 inhibitor for the treatment of diabetes in the context of type A IR syndrome.
Glucagon-Like peptides, glucagon-like peptide-1 receptor agonist, Glucagon-Like Peptides, Péptidos similares al glucagón, Resistencia a la insulina, Diseases of the endocrine glands. Clinical endocrinology, Type A insulin resistance syndrome, Compuestos de bencidrilo, Diabetes mellitus, Endocrinology, Glucosides, insulin resistance, Insulina, Diabetes Mellitus, Humans, Insulin, Benzhydryl Compounds, Glucósidos, diabetes, Benzhydryl compounds, Insulin resistance, RC648-665, sodium-glucose cotransporter 2 inhibitor, Insulin Resistance
Glucagon-Like peptides, glucagon-like peptide-1 receptor agonist, Glucagon-Like Peptides, Péptidos similares al glucagón, Resistencia a la insulina, Diseases of the endocrine glands. Clinical endocrinology, Type A insulin resistance syndrome, Compuestos de bencidrilo, Diabetes mellitus, Endocrinology, Glucosides, insulin resistance, Insulina, Diabetes Mellitus, Humans, Insulin, Benzhydryl Compounds, Glucósidos, diabetes, Benzhydryl compounds, Insulin resistance, RC648-665, sodium-glucose cotransporter 2 inhibitor, Insulin Resistance
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