Medical Therapy for Pediatric Pulmonary Arterial Hypertension
Copyright policy )Medical Therapy for Pediatric Pulmonary Arterial Hypertension
Pulmonary arterial hypertension (PAH) is a life-threatening disease, the prognosis of which has changed dramatically in the past decade since the introduction of new therapeutic agents and the off-label application of adult pulmonary hypertension (PH)-specific therapies to children.1–3 However, PAH still has no cure, and the aim of treatment is to prolong survival by improving quality of life, symptoms, exercise capacity, and hemodynamics. The selection of appropriate therapies for pulmonary hypertension is complex, and they must be carefully chosen according to the etiology and pulmonary vasoreactivity.3 As insight advances into mechanisms responsible for the development of PAH, we hope the introduction of novel therapeutic agents will further improve the outcome of this disease.
- University of Geneva Switzerland
- University Hospital of Geneva Switzerland
- University of Colorado Denver United States
Lung Diseases, Epoprostenol/*therapeutic use, Phosphodiesterase Inhibitors, Hypertension, Pulmonary, Lung Diseases/epidemiology, Hypertension, Pulmonary/diagnosis/*drug therapy/epidemiology, Anemia, Sickle Cell, Phosphodiesterase 5 Inhibitors, Epoprostenol, Severity of Illness Index, 618, Anemia, Sickle Cell/epidemiology, Chronic Disease, Phosphodiesterase Inhibitors/*pharmacology/*therapeutic use, Humans, Child, Antihypertensive Agents/*therapeutic use, Algorithms, Antihypertensive Agents, ddc: ddc:618
Lung Diseases, Epoprostenol/*therapeutic use, Phosphodiesterase Inhibitors, Hypertension, Pulmonary, Lung Diseases/epidemiology, Hypertension, Pulmonary/diagnosis/*drug therapy/epidemiology, Anemia, Sickle Cell, Phosphodiesterase 5 Inhibitors, Epoprostenol, Severity of Illness Index, 618, Anemia, Sickle Cell/epidemiology, Chronic Disease, Phosphodiesterase Inhibitors/*pharmacology/*therapeutic use, Humans, Child, Antihypertensive Agents/*therapeutic use, Algorithms, Antihypertensive Agents, ddc: ddc:618
selected citations These citations are derived from selected sources.This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).39 popularity This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.Top 10% influence This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).Top 10% impulse This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.Top 10%
Citations provided by BIP!Popularity provided by BIP!