Bone screws are vital for orthopedic procedures but often lead to issues like dislocation and bone problems. Current testing with cadaver bones is slow and lacks consistency [1,2]. Computer simulations provide a faster, cost-effective way to assess screw designs and reduce the need for human samples. Numerical models consider factors like geometry and materials but struggle with bone variability [3]. Micro finite element analysis shows promise but needs to accurately represent non-linear effects and the bone-screw interface. Few studies have compared numerical models to mechanical tests, especially concerning stiffness and strength [4]. This study aims to quantify pull-out characteristics of bone screw in both homogenized and non-homogenized material.