Nettle is a perennial plant rich in phytochemicals and specialized metabolites (SM), often categorized as a product of great potential and wide usage. Although wild nettle is widespread in nature, its cultivation is necessary in order to achieve known chemical composition of final product. Agro-technical measures during different phases in plants development can considerably impact the synthesis and accumulation of SM, which are directly influenced by numerous biotic, abiotic and anthropogenic factors. Key factors for obtaining a nutritive high quality product of adequate yield include balanced fertilization, plant development stage and harvest period. More evident climatic changes encourage the implementation of modern growing methods. Modern vegetables growing methods include hydroponic cultivation which shows number of advantages: good natural resources management, rationalized water consumption because of nutrient solution recirculation, preventing loss of nutrients from the rhizosphere, control of abiotic factors of nutrient solution and air. During the product market placement with an aim of longer nutritive and organoleptic qualities preservation and durability of the product it is necessary to pack the product with a goal to reduce the contact of fresh nettle with the surrounding atmosphere. Key factors during packaging are selection of adequate packaging material and gases composition in package. Packaging in a modified atmosphere significantly reduces the degradation of nutritional properties of fresh plant material while ensuring the microbiological safe of the packaged product.