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Release for the publication: @article{marzahl2021MultipleSpecies, author = {Christian Marzahl and Jenny Hill and Jason Stayt and Dorothee Bienzle and Lutz Welker and Frauke Wilm and J{\"{o}}rn Voigt and Marc Aubreville and Andreas K. Maier and Robert Klopfleisch and Katharina Breininger and Christof A. Bertram}, title = {Inter-Species Cell Detection: Datasets on pulmonary hemosiderophages in equine, human and feline specimens}, journal = {CoRR}, volume = {abs/2108.08529}, year = {2021}, url = {https://arxiv.org/abs/2108.08529}, abstract = {Pulmonary hemorrhage (P-Hem) occurs among multiple species and can have various causes. Cytology of bronchoalveolarlavage fluid (BALF) using a 5-tier scoring system of alveolar macrophages based on their hemosiderin content is considered the most sensitive diagnostic method. We introduce a novel, fully annotated multi-species P-Hem dataset which consists of 74 cytology whole slide images (WSIs) with equine, feline and human samples. To create this high-quality and high-quantity dataset, we developed an annotation pipeline combining human expertise with deep learning and data visualisation techniques. We applied a deep learning-based object detection approach trained on 17 expertly annotated equine WSIs, to the remaining 39 equine, 12 human and 7 feline WSIs. The resulting annotations were semi-automatically screened for errors on multiple types of specialised annotation maps and finally reviewed by a trained pathologists. Our dataset contains a total of 297,383 hemosiderophages classified into five grades. It is one of the largest publicly availableWSIs datasets with respect to the number of annotations, the scanned area and the number of species covered.} eprinttype = {arXiv}, eprint = {2108.08529}, timestamp = {Mon, 23 Aug 2021 14:07:13 +0200}, biburl = {https://dblp.org/rec/journals/corr/abs-2108-08529.bib}, bibsource = {dblp computer science bibliography, https://dblp.org} }
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