This is the fourth release of the seqCAT package, which follows Bioconductor's "even-release, odd-devel" version scheme and is equivalent to the 1.6.0 release on the Bioconductor website. It includes the following additions and changes: Rename several function arguments to increase clarity Make filtering of variant calling-specific quality metrics optional Add a check to validate if input VCFs are genomic VCFs Add checks to validate if input VCFs contain data on variant depth, allelic depth and genotype data