
eidolon is a Rust port and extension of NEAT that generates simulated next-generation sequencing data in FASTQ and VCF formats with the statistical properties of real datasets, along with a golden BAM/VCF truth set of inserted variants and ideal alignments. It adds structural-variant simulation (CNV, BND, INV, INS, and others) and an end-to-end tumor/normal cancer workflow (gen-cancer-reads) that merges two read passes at a configurable purity and emits an origin-tagged truth VCF for benchmarking somatic and structural-variant callers, with an emphasis on low memory use and short CPU time.
If you use this software, please cite it using the metadata from this file.
variant-calling, cancer-genomics, fastq, vcf, bioinformatics, rust, ngs-simulation, structural-variants
variant-calling, cancer-genomics, fastq, vcf, bioinformatics, rust, ngs-simulation, structural-variants
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