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Hedgehog pathway activity and ICB signature correlation in ovarian cancer scRNA-seq (GSE130000)

integration_instructionsResearch softwarekeyboard_double_arrow_right Software 04 Jun 2026Publisher:Zenodo
Authors: Karthikeyan, Mythreye;

doi: 10.5281/zenodo.20542282 , 10.5281/zenodo.20542281

Hedgehog pathway activity and ICB signature correlation in ovarian cancer scRNA-seq (GSE130000)

Abstract

This release contains: R scripts for Hedgehog pathway scoring and ICB signature correlation analysis in the GSE130000 ovarian cancer scRNA-seq dataset (Kan et al., Oncogene 2022). Result tables (CSV) for all correlation analyses. Main and supplementary figures (PDF + PNG). Reproducibility metadata (sessionInfo.txt, CITATION.cff). Source expression data are not redistributed; download from TISCH2 (OV_GSE130000) per the instructions in README.md.

If you use this code, please cite the associated manuscript and this repository.

Keywords

TISCH2, single-cell RNA-seq, ovarian cancer, GSE130000, Hedgehog signaling, immune checkpoint blockade

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selected citations
These citations are derived from selected sources.
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
0
Average
Average
Average
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Cancer Research