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ZENODO
Software . 2023
Data sources: ZENODO
ZENODO
Software . 2023
Data sources: Datacite
ZENODO
Software . 2023
Data sources: Datacite
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Pasa: Leveraging population pangenome graph to scaffold prokaryote genome assemblies

Short-read scaffolder software
Authors: Do, Van Hoan; Nguyen, Son Hoang; Le, Duc Quang; Nguyen, Tam Thi; Nguyen, Canh Hao; Ho, Tho Huu; Vo, Nam S.; +3 Authors

Pasa: Leveraging population pangenome graph to scaffold prokaryote genome assemblies

Abstract

Illumina short-read assemblies for microbial genomes are normally suffered from fragmentation due to repetitive elements that require long reads or close reference genomes to resolve. While long-read sequencing data is not always available, reference-based methods are usually subject to the bias problem which can be severe for highly diversified strains.To tackle this issue, we use the pangenome graph built from a large set of multiple related genomes to guide the scaffolding process of a bacterial strain genome assembly. We propose Pasa, a graph-based algorithm framework that can utilize the pangenome graph and the assembly graph information to improve scaffolding quality.

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selected citations
These citations are derived from selected sources.
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
0
Average
Average
Average