Introduction: Achilles tendinopathy (AT) is characterized by pain, inflammation, and functional limitations.It is also the most common cause of pain located at the back of the calcaneus. The Achilles tendon is amongthe most vulnerable tendons in the lower limb, and its pathology is one of the most common overuseinjuries. Moreover, it is not an injury exclusive to athletes, as 65% of diagnosed Achilles tendinopathies arenot related to sport.Methods: Randomized, single-blind clinical trial with 60 patients, 30 in each group. All study participantswere previously diagnosed with insertional AT, mid-portion tendinopathy, or both and were referred by anorthopedic surgeon. The short- and medium-term results of treatment with dry needling (DN) application tothe gastrocnemius muscle trigger points (MTrPs) versus ultrasound-guided percutaneous electrolysis (PE)application to the Achilles tendon were observed in terms of pain intensity, pressure pain threshold, ankledorsiflexion range of motion under load, quality of life, and ankle and foot function in patients withpreviously diagnosed AT.Results: The visual analogue scale revealed that the time effect was statistically significant. Similarly, ATalgometry revealed that the time effect was statistically significant, indicating that the pressure painthreshold assessed by algometry changed significantly over the course of the study. Moreover, quality of lifeand functionality showed statistically significant improvements from the third week of the study, whereasrange of motion remained unchanged.Conclusion: Ultrasound-guided PE applied to the Achilles tendon is more effective than DN applied to theMTrPs of the gastrocnemius muscle in reducing pain intensity and improving quality of life and ankle andfoot function in the short and medium term in patients with AT.