The faunistic review of Lepidoptera, Heterocera in the eastern Serbia area, with ecological characteristics and zoogeographical distribution is presented. Author gives details of Lepidoptera species collected in the years 1998, 2014 and 2016 respectively. In total, 44 species are registered, of which there were 1Tineidae, 1 Limacodidae, 1 Cossidae, 1 Pterophoridae, 1 Thyrididae, 2 Lasiocampidae, 1 Sphingidae, 1 Drepanidae, 13 Geometridae, 4 Notodontidae, 8 Erebidae, 8 Noctuiodae and 1 Nolidae species. Some of them show narrow distribution, of which 15 are recorded for the second, or third, time in Serbia. Illustration of some habitats, adults and genitalia slides are given.