Acharya Sushruta mentioned maximum retention period of snehika basti is up to nine hours. If snehika basti retains for maximum time, then it’s very effective. This is probably because there is enough time for absorption of the Sneha. Acharya Sushruta has stated that the action of basti is mainly due to its virya (specific action or property). He further elaborates that the drugs used in basti spread in the body from pakwashaya through appropriate channels; similarly as a tree gets irrigated at the root and nutrients circulate to all parts of the tree. Basti eliminates the morbid dosha from the entire body (i.e. from rasa dhatu to shukra dhatu) gradually and all dhatus get nourishment as per Sushruta. This is possible when basti retains inside for maximum duration. The management of osteoarthritis of knee is broadly divided into non-pharmacological, pharmacological, and surgical treatments. These treatments are either expensive or not available for common people in developing countries. Basti treatment is useful in such patients, especially in elderly persons having natural predominance of vata dosha in their body. As sesame oil [tila taila] possesses having specific properties like snigdha, ushna, madhur, kashaya, tikta rasa & is ushna guna in nature, hence it diminishes vitiated vata and removes kapha. Addition of powders of shatavaha and sandhaiv in sesame oil used for basti, helps the maximum retention of matrabasti, so its useful in managing dhatkshyatmka janusandhigata vata.