In this dataset, the water depth time series in 21 gauges of Sumacarcel town are derived by the FLOW-R2D model, assuming 240 different combinations of three input paramaters: a) input flow to the computatioal domain (upstream boundaries) (Q) b) the Manning coefficient of the computational domain (n) c) effective slope (required at the upstream boundaries) (S) The sampling for the three parameters is made by Latin Hypercube technique, assuming for each parameter the following interval: a) 10000-20000 m^3/s b) 0.03-0.21 s/m^(1/3) c) 0.0001 - 0.02 The dataset consists of the following: 1) input_data.csv file, in which the 240 combinations of the three input parameters is provided (Scenario 100 - 399) 2) runs_tous folder, in which files 100.cv-399.csv. Water depth time series are recorded in 21 gauges. The first column is time (in seconds), and the water dpeths are in meters. Papers relative to this dataset: 1) Description of the case study: Alcrudo F and Mulet J (2007). Description of the Tous Dam break case study (Spain). Journal of Hydraulic Research, 45, 45-57. 2) Simulation of tous dam break with FLOW-R2D: Bellos V and Tsakiris G (2015). 2D flood modelling: the case of Tous dam break. Proceedings of 36th World Congress of IAHR, the Hague, the Netherlands. (e-proceedings). 3) Calibration of the case study of the FLOW-R2D paramteters: Christelis V, Bellos, V, Tsakiris, G (2016). Employing surrogate modelling for the calibration of a 2D flood simulation model. Proceedings of 4th European Congress of IAHR, “Sustainable Hydraulics in the era of global change”, edited by S. Erpicum, B. Dewals, P. Archambeau, M. Pirotton, Liege, Belgium: 727-732. 4) Presentation of the FLOW-R2D model: Tsakiris G and Bellos, V (2014) A numerical model for two-dimensional flood routing in complex terrains. Water Resources Management 28(5):1277-1291