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Figure S1. Forest plot of the association of Vit D on CHB (A), Vit D on CHC (B), 25-OHD on CHB (C), 25-OHD on CHC (D). Vit D, vitamin D; 25-OHD, 25-hydroxyvitamin D; CHB, chronic hepatitis B; CHC, chronic hepatitis C. Figure S2. LOO sensitivity analysis of the association of Vit D on CHB (A), Vit D on CHC (B), 25-OHD on CHB (C), 25-OHD on CHC (D). Vit D, vitamin D; 25-OHD, 25-hydroxyvitamin D; CHB, chronic hepatitis B; CHC, chronic hepatitis C. Figure S3. Scatter plots showing the causal effect of Vit D on CHB (A), Vit D on CHC (B), 25-OHD on CHB (C), 25-OHD on CHC (D). Vit D, vitamin D; 25-OHD, 25-hydroxyvitamin D; CHB, chronic hepatitis B; CHC, chronic hepatitis C. Figure S4. Funnel plot of the association of Vit D on CHB (A), Vit D on CHC (B), 25-OHD on CHB (C), 25-OHD on CHC (D). Vit D, vitamin D; 25-OHD, 25-hydroxyvitamin D; CHB, chronic hepatitis B; CHC, chronic hepatitis C. Figure S5. Forest plot of the association of CHB on Vit D (A), CHC on Vit D (B), CHB on 25-OHD (C), CHC on 25-OHD (D). Vit D, vitamin D; 25-OHD, 25-hydroxyvitamin D; CHB, chronic hepatitis B; CHC, chronic hepatitis C. Figure S6. LOO sensitivity analysis of the association of CHB on Vit D (A), CHC on Vit D (B), CHB on 25-OHD (C), CHC on 25-OHD (D). Vit D, vitamin D; 25-OHD, 25-hydroxyvitamin D; CHB, chronic hepatitis B; CHC, chronic hepatitis C. Figure S7. Scatter plots showing the causal effect of CHB on Vit D (A), CHC on Vit D (B), CHB on 25-OHD (C), CHC on 25-OHD (D). Vit D, vitamin D; 25-OHD, 25-hydroxyvitamin D; CHB, chronic hepatitis B; CHC, chronic hepatitis C. Figure S8. Funnel plot of the association of CHB on Vit D (A), CHC on Vit D (B), CHB on 25-OHD (C), CHC on 25-OHD (D). Vit D, vitamin D; 25-OHD, 25-hydroxyvitamin D; CHB, chronic hepatitis B; CHC, chronic hepatitis C. Table S1. Baseline characteristics of Vit D and CH dataset in the present study. Table S2. MR results between Vit D and CH. Table S3. Pleiotropy and heterogeneity test between Vit D and CH.
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