Pure and magnesium/nano hydroxyapatite (HAp) prepared by microwave route. The sample was analyzed by X-Ray Diffraction (XRD), photoluminescence (PL) and bioactivity. The XRD analysis was revealed that pure phase of HAp. As the concentration of magnesium ion increases, the average crystallite was reduced. The PL and in vitro bioactivity of the doped sample were enhanced. Hence, magnesium based calcium phosphate could be a suitable candidate for multifunctional applications.