This is a complete dataset from a study aimed to establish a predictive model for neoadjuvant chemoradiotherapy (nCRT) response in patients with locally advanced rectal carcinoma (LARC) using clinicopathological and radiomics features from pretreatment MRI 3D T2W contrast sequence scans. This dataset contains the outcome defined as cCR, TRG1, TRG2, TRG3 and TRG4, five clinicopathological and MRI parameters which significantly associated with the outcome and all of the computed 2144 radiomics features. All this data is available for 71 patients without any missing values. All data is z-score normalized.