This dataset contains raw free induction decay (FID) signals collected during 1H magnetic resonance spectroscopy (MRS) study in 52 individuals with tinnitus (24 with unilateral and 28 with bilateral tinnitus) and 25 healthy volunteers (described in detail in a separate article doi:10.1038/s41598-023-45024-3). Data acquisition was performed using 3T Siemens Prisma Fit scanner with a 20-channel receiver head-coil. A single voxel spectroscopy (SVS) PRESS (Point-Resolved Spectroscopy Sequence) sequence was applied for collection of MRS data, using standard Siemens water suppression (water saturation, 50 Hz bandwidth) and no lipid suppression. MRS data was collected from four cubic 3.75 cm3 (1.5 cm x 1.5 cm x 1.5 cm) regions-of-interest in the brain, placed in the left temporal lobe, right temporal lobe, left frontal lobe, and right frontal lobe. The MRS sequence parameters were: TR (time of repetition) = 2000 ms, TE (time of echo) = 40 ms, TA (time of acquisition) = 4 min 26 s, 128 averages with 1024 time points and 1200 Hz bandwidth. MRS data is stored in RDA file format, developed by Siemens (see doi:10.1002/nbm.4257, Table 1). Each RDA file contains a text header (which can be viewed using a standard notepad application) and binary FID signal under the header. Data can be imported for analysis using several open-source packages (tested with FID-A doi:10.1002/mrm.26091 and spant doi:10.21105/joss.03646). Naming scheme of files is as follows: __.rda For example: 001_L_F.rda is data from participant 001 collected from a voxel placed in a ROI in the left frontal lobe. In order to allow replication of the results from the original article, we also added information about the group of each of the subjects. This information is stored in a TSV file containing two columns: participant_ID and group (C – control, TU – unilateral tinnitus, TB – bilateral tinnitus). Aside from replication of our results this dataset may be used e.g. for testing of different MRS data processing pipelines.

Contact details: Prof. Tomasz Wolak, head of Bioimaging Research Center of Institute of Physiology and Pathology of Hearing (t.wolak@ifps.org.pl)