The aim of the proposed study was to collect the useful information of the traditional medicinal plant Trichodesma indicum and upgrade the knowledge about the plant. It belongs to family Boraginaceae. Pharmacognostic studies of plant drug are carried out for the evaluation of drug and to detect the adulteration. It includes dermal characters like stomata, trichomes and anatomical features. Phytochemical studies of this plant shows presence of steroids, triterpenoids, tannins, flavonoids, saponins etc. In the formulative studies, cream has been prepared and shows with good washability, solubility and smooth greasy texture. Ethanobotanical studies shows various uses such as anti-inflammatory, antimitotic, antioxidant, anti-diabetic etc.