The SUDMEX_TMS dataset is the result of a longitudinal clinical trial of cocaine use disorder patients that were treated with rTMS at 5-Hz on the left dorsolateral prefrontal cortex (lDLPFC) for a 2 week double-blind acute phase and an open-label maintenance phase that included clinical, cognitive and MRI data acquisition. The design was a double-blind placebo-controlled randomized controlled trial with parallel groups (acute phase). The study was done at the National Institute of Psychiatry . Each patient had more than one clinical and MRI session or time point from baseline (T0), 2 weeks (T1), 3 months (T2), 6 months (T3) and some patients had 12 months (T4). The T14 time point was only for patients in the Sham group who decided to continue the clinical trial with open-label rTMS. The T14 refers to 2 weeks after T1 (4 weeks after T0). The MRI sequences were: 1) T1-weighted, 2) rsfMRI 10 min, 3) HARDI-DWI multishell (next release). The data set is curated and organized by test and item for each experimental phase and also has a dictionary to define the variables measured. If you require more information about data or scales, please contact us. LANIREM (National MRI Laboratory), Institute of Neurobiology, Universidad Nacional Autónoma de México (UNAM), Querétaro, México. Diego Angeles Valdez, M. Sc. diego.ang.val@gmail.com diego.ang.val@inb.unam.mx Eduardo A. Garza-Villarreal, M.D., Ph.D. egarza@gmail.com egarza@comunidad.unam.mx