Morocco is located in a risky geographical area: the ibero-maghrebi Mediterranean zone, which is situated on the “seismic belt”, known for its seismic instability and comprising high risk areas. Each year, hundreds of earthquakes of different magnitudes are recorded by seismic surveillance stations belong to the National Institute of Geophysics. The aim of this paper is to study the influence of Spectral Responses on the Structures as well as to make a comparison with the requirements of the Moroccan seismic construction regulations (RPS) 2000 revised in 2011 in the case of the Rhiss river earthquake saved in seismogenic source 4 (Rif Oriental - Al Hoceima - Alboran).