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Peripheral Ossifying Fibroma- A Clinical and Histological Evaluation of 51 Cases

Authors: Pushparaja Shetty; Adyanthaya, Soniya;

Peripheral Ossifying Fibroma- A Clinical and Histological Evaluation of 51 Cases

Abstract

{"references": ["1. Bhaskar SN, Jacoway JR: Peripheral fibroma and peripheral fibroma with calcification; report of 376 cases. Journal of American Dental Association, 1966;73(6) :1312-1320.", "2. Bodner L, Dayan D: Growth potential of peripheral ossifying fibroma. Journal of Clinical Periodontology, 1987;14(9):551\u2013554.", "3. Brown FH, Houston GD: Differential diagnosis of localized tumors of the gingival. Compendium, 1990;11(12):702-704.", "4. Buchner A, Hansen LS: The histomorphologic spectrum of peripheral ossifying fibroma. Oral Surgery Oral Medicine Oral Pathology, 1987;63(4):452-461.", "5. Cuisia ZE, Brannon RB: Peripheral ossifying fibroma- a clinical evaluation of 134 pediatric cases. Pediatric Dentistry, 2001;23(3):245-248.", "6. Das S, Das AK: A review of pediatric oral biopsies from a surgical pathology service in a dental school. Pediatrics Dentistry, 1993;15(3):208\u2013211.", "7. Eversole LR, Rovin S: Reactive lesions of the gingiva. Journal of Oral Pathology, 1972;1(1):30\u201338", "8. Flaitz CM: Peripheral giant cell granuloma: a potentially aggressive lesion in children. Pediatric Dentistry, 2000;22(3):232-233.", "9. Gardner DG: The peripheral odontogenic fibroma; an attempt at clarification. Oral Surgery Oral Medicine & Oral Pathology, 1982;54(1):40-48.", "10. Gracia de Marcos JA, Gracia de Marcos MJ, Rodriguez SA, Rodrigo JC, Poblet E: Peripheral ossifying fibroma: a clinical and immunohistochemical study of 4 cases. Journal of Oral Science, 2010;52(1): 95-99.", "11. Kendrick F, Waggoner WF: Managing a peripheral ossifying fibroma. ASDC Journal of Dentistry Children, 1996;63(2):135-138.", "12. Kenny JN, Kaugars GE, Abbey LM: Comparison between the peripheral ossifying fibroma and peripheral odontogenic fibroma. Journal of Oral and Maxillofacial Surgery, 1989; 47(4): 378-382.", "13. Kohli K, Christian A, Howell R: Peripheral ossifying fibroma associated with a neonatal tooth: case report. Pediatric Dentistry, 1998;20(7):428\u2013429.", "14. Kumar SK, Ram S, Jorgensen MG, Shuler CF, Sedghizadeh PP: Multicentric peripheral ossifying fibroma. Journal of Oral Science, 2006;48:239-243.", "15. MacDonald-Jankowski DS: Fibro-osseous lesions of the face and jaws. Clinical Radiology, 2004;59(1):11\u201325.", "16. Miller CS, Henry RG, Damm DD: Proliferative mass found in the gingiva. Journal of American Dental Association, 1990; 121(4):559-560.", "17. Moon WJ, Choi SY, Chung EC, Kwon KH, Chae SW: Peripheral ossifying fibroma in the oral cavity: CT and MR findings. Dentomaxillofacial Radiology, 2007;36(3):180-182.", "18. Poon CK, Kwan PC, Chao SY: Giant peripheral ossifying fibroma of the maxilla: report of a case. Journal of Oral Maxillofacial Surgery, 1995;53(6):695\u2013698.", "19. Shamim T, Varghese VI, Shameena PM, Sudha S: A retrospective analysis of gingival biopsied lesions in south Indian population: 2001-2006. Medicina Oral Patologia Oral Cirugia Bucal, 2008;13(7):E414-18.", "20. Skinner RL, Davenport WD (Jr), Weir JC, Carr RF: A survey of biopsied oral lesions in pediatric dental patients. Pediatric Dentistry, 1986;8(2):163\u2013167.", "21. Southam JC, Venkataraman BK: Calcification and ossification in epulides in man (excluding giant cell epulides). Archives of Oral Biology, 1973;18(10):1243- 1253.", "22. Speight PM, Carlos R: Maxillofacial fibro-osseous lesions. Current Diagnostic Pathology, 2006;12(1):1\u2013 10.", "23. Walters JD, Will JK, Hatfield RD, Cacchillo DA, Raabe DA: Excision and repair of the peripheral ossifying fibroma: a report of 3 cases. Journal of Periodontology, 2001; 72(7):939-944.", "24. Whitaker SB, Bouquot JE: Estrogen and progesterone receptor status of central giant cell lesions of the jaws. Oral Surgery, Oral Medicine & Oral Pathology, 1994;77(6):641-644", "25. Wright BA, Jennings EH: Oxytalan fibers in peripheral odontogenic fibromas: A histochemical study of 18 cases. Oral Surgery, Oral Medicine & Oral Pathology, 1979;48(5):451-453", "26. Yadav R, Gulati A: Periphearl ossifying fibroma: a case report. Journal of Oral Science, 2009;51(1):151-154.", "27. Yip WK, Yeow CS: A congenital peripheral ossifying fibroma. Oral Surgery Oral Medicine & Oral Pathology, 1973;35(5):661\u2013666.", "28. Zain RB, Fei YJ: Fibrous lesions of the gingiva: a histopathologic analysis of 204 cases. Oral Surgery Oral & Medicine Oral Pathology, 1990;70(4):466\u2013470.", "29. Zhang W, Chen Y, An Z, Geng N, Bao D: Reactive gingival lesions: a retrospective study of 2,439 cases. Quintessence International, 2007;38(2):103\u2013110."]}

The present retrospective study was carried out to investigate the clinical and histological features of 51 cases of peripheral ossifying fibroma (POF). The clinical information such as age, sex, location, color of the lesion, pedunculated/ sessile was recorded. The lesion was found more frequently in females (62.75%) and 2nd decade. It had a predilection for the maxillary gingiva (68.63%) and the incisor/cuspid region (72.55%). The average age of occurrence was 38.5 years. Histologically, the surface epithelium was ulcerated in 15(29.41%) cases and in the rest, it was non-ulcerated. The lesion exhibited highly cellular fibroblastic tissue in 12(23.53%) cases, and in the remaining cases it showed more fibrous tissue. Mineralized products in the form of trabeculae of woven and/ or lamellar bone (61%), cementum like material (12%) and dystrophic calcification (27%) were noticed.

Keywords

Mineralization, Dystrophic calcification, Trabeculae, Peripheral ossifying fibroma, Cementum like material

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This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
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