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Bilateral Testicular Metastases of Adenoid Cystic Variant of Carcinoma of Prostate

Authors: Anita AM; Sainath K Andola; Rachana Lakhe;

Bilateral Testicular Metastases of Adenoid Cystic Variant of Carcinoma of Prostate

Abstract

{"references": ["1. Pujari NR. Prevalence of Prostate Carcinoma in the Indian Population: The Need to Revise Serum Prostate Specific Antigen (PSA). Uro Today Int J 2001;6(4):art 51. http:// dx.doi.org/10.3834/uij.1944-5784.2013.08.10", "2. Kulkarni S, Coup A, Kershaw JB, Buchholz NPN. Metastatic appendiceal adenocarcinoma presenting late as epididymo-orchitis: a case report and review of literature. BMC Urology 2004;4:1-4", "3. Lalitha K, Suman G, Pruthvish S, Mathew A, Murthy NS. Estimation of Time Trends of Incidence of Prostate Cancer \u2013 an Indian Scenario. Asian Pacific J Cancer Prev 2012;13(12):6245-50.", "4. Lu L, Kuo JY, Lin ATL, Chang Y, Chen K, Pan C, et al. Metastatic Tumors Involving the Testes. J Urol Roc 2000; 11(1):12-17.", "5. Akbal CEM, Erdem E, Hamada H, Uygur MC, Ozen H. Prostatic cancer with metastasis to the testis. Turkish Journal of Cancer 2001;31(1):35-8.", "6. Haupt B, Ro JY, Ayala AG, Zhai J. Metastatic Prostatic Carcinoma to Testis: Histological Features Mimicking Lymphoma . Int J Clin Exp Pathol 2009; 2:104-07", "7. Quinn M, Babb P. Patterns and trends in prostate cancer incidence, survival And mortality, part I: international comparisons. Br J Urol Int 2002;90:162\u2013 73.", "8. Begnami MD, Quezado M, Pinto P, Linehan WM, Merino M. Adenoid Cystic/Basal Cell Carcinoma of the Prostate Review and Update. Arch Pathol Lab Med 2007;131:637\u201340", "9. Iczkowski KA, Ferguson KL, Grier DD. Adenoid cystic/ basal cell. Carcinoma of the prostate: clinicopathologic findings in 19 cases.Am J Surg Pathol 2003;27:1523\u201329.", "10. Mckenney JK, Amin MB, Srigley JR, Jimenez RE, Ro JY, Grignon DJ, et al. Basal cell proliferations of the Prostate other than usual basal cell hyperplasia: a clinicopathologic study of 23 Cases, including four carcinomas, with a proposed classification. Am J Surg Pathol 2004;28:1289\u201398.", "11. Luebke AM, Schlomm T, Gunawan B, Bonkhoff H, Fuzesi L, Erbersdobler A. Simultaneous tumour-like, atypical basal cell hyperplasia and acinar adenocarcinoma of the prostate: a comparative morphological and genetic approach.Virchows Arch 2005;446:338\u201341."]}

Prostate cancer is the second most frequently diagnosed cancer in men (13.6%) and the fifth most common cancer globally.Common sites of prostate carcinoma metastasis other than lymph nodes, include bones, lungs, urinary bladder, liver and adrenal glands. Rarely, a testicular mass, whether painful or painless, represents a metastasis. Metastasis in testes accounts for 0.06-2.5%. Bilateral testicular metastasis is less common and occurs in about 15% of cases. We report a case of prostatic adenocarcinoma in a 65 year male with metastasis to both testes identified upon histopathological examination of therapeutic orchidectomy specimen. Unusual adenoid cystic pattern seen in the metastatic deposits is highlighted. Bilateral metastasis is extremely rare and few are reported in literature.

Keywords

prostate, orchidectomy, metastasis, Adenocarcinoma

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This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
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