{"references": ["1. Yadav NK, Santhian B, Kalai RS. Assessment of Diabetes Mellitus in India and Nepal 2012;3(6)", "2. Dabla PK. Renal function in diabetic nephropathy. WJD. 2010 ; 1(2): 48-56.", "3. Bhat RM, Ganaraja B. A study of renal function tests in South Indian diabetic population. Journal of Pharmacy Research. 2011; 4(12): 4470-72", "4. Sacks DB, Bruns DE, Goldstein DE, Maclaren NK and McDonald JM. Guidelines and recommendations for laboratory analysis in the diagnosis and management of diabetes mellitus. ClinChem 2002; 48(3): 436-72.", "5. Jha P, Das BKL, Shreshtha S, Majhi S, Chandra L. Sharma S et al. Glycaemic status, lipid profile and proteinuria in diabetic nephropathy. JNepal Med Assoc 2012; 49(178): 43-6.", "6. Moore DJ, Gregory JM, Kumah-Crystal YA, Simmons JH. Mitigating micro- and macro-vascular complications of diabetes beginning in adolescence. Vasc Health Risk Manag 2009; 5: 1015-31.", "7. Spanou E, Krantzis I, Iatrou C. Microalbuminuria and diabetic nephropathy: epidemiology, prognostic significance and prevention. Archives of Hellenic Medicine 2009 ; 26(3):316-30", "8. Chowta NK, Pant P, Chowta MN. Microalbuminuria in diabetes mellitus: association with age, sex, weight and creatinine clearance. Indian J Nephrol 2009;19(2): 53- 56.", "9. Use of glycated haemoglobin and microalbuminuria in the monitoring of diabetes mellitus. Summary, Evidence report/Technology Assessment: Number 84. AHRQ, 2003. Available from: http://www.ahrq.gov/clinic/ epcsums/glycasum.htm", "10. Kanakamani J, Ammini AC, Gupta N, Dwivedi SN. Prevalence of microalbuminuria among patients with type 2 diabetes mellitus. Diabetes Technology and Therapeutics 2010 ;12(2): 161-6.", "11. Maskari FA, Sadig ME, Obineche E. Prevalence and determinants of microalbuminuria among diabetic patiens in the United Arab Emirates. BMC Nephrology. 2008;9:1. Available from: http://www.biomedcentral.com/ 1471-2369/9/1", "12. Al-Sheikh A. Prevalence of microalbuminuria in type 2 diabetes mellitus at a diabetic clinic in Abualaziz university hospital. Pak J Med Sci 2000; 23(2): 223-6.", "13. Muraliswaran P, Aparna G, Kanagavalli P, Srikanth S. Prevalence of microalbuminuria in relation to HbA1c among known type 2 diabetic patients in Puducherry population. RJPBCS 2013 ; 4(1): 458-62.", "14. Verghese A, Deepa R, Rema M, Mohan V. Frequency of proteinuria in type 2 diabetes mellitus seen at a diabetic centre in south India. Postgrad Med J 2001; 77:399-402.", "15. Choo-Kang E, Reid HL. Microalbuminuria in diabetes mellitus. Prio Onl J 2008.", "16. Naveen P, Annam N, Apnam V, Prakash BG, Kumar AR. Evaluation of glycated haemoglobin and microalbuminuria as early markers of nephropathy in type 2 diabetes mellitus. IJBMR. 2012; 3(2): 1724-6", "17. Maiti A, Raichaudhuri P, De J, Mukhopadhaya S, et al. Changes in microalbuminuria in relationship to glycosylated haemoglobin and duration of type 2 diabetes mellitus. Indian Medical Gazette 2012 ;(2): 394- 99", "18. Afkhami-Ardekani M, Modarresi M, Amirchaghmaghi E. Prevalence of microalbuminuria and its risk factors in type 2 diabetes. Ind J Nephrol 2008;18(3):112-17.", "19. Bloom DE, Cafiero ET, Jane -Llopis E, Abrahams GS, Bloom LR, Fathima S, et al. The global economic burden of non-communicable diseases : Geneva : World Economic Forum; 2011", "20. Moore DJ, Gregory JM, Kumah-Crystal YA, Simmons JH. Mitigating micro- and macro-vascular complications of diabetes beginning in adolescence. Vascular Health and Risk Management. 2009;5: 1015-31."]}

Nephropathy is a common complication of Diabetes Mellitus that could lead to End Stage Kidney Disease (ESKD). Microalbuminuria is important as an ‘early marker’ of renal disease as it represents a time when renal biopsy shows no or minimal changes. Glycosylated Hemoglobin (HbA1c) represents the average glucose concentration over the period of 2-3 months and is accepted as a useful index of mean blood glucose. The purpose of the study was to study the relationship between HbA1c and urinary microalbumin in patients of type 2 diabetes mellitus. A prospective study was conducted on 200 known diabetics. Detailed history was taken and thorough physical examination of all the patients was done followed by HbA1c estimation by Bio Rad D10 HPLC machine and microalbumin by Nyco Card Microalbumin test kit. Statistical analysis was done using Karl Pearson’s correlation using SPSS software version 19. 56.5% of the cases were males and 43.5% females. 43.5% cases were positive for microalbumin, of which 47% had duration of diabetes between 5 to 10 years (p<0.05). 35% cases had HbA1c in the range of 8.1-10% of which 67% had microalbuminuria (p<0.05) . Microalbuminuria showed a significant correlation with HbA1c and duration of diabetes, thus serving as an invaluable tool in monitoring of glycaemic status and screening for diabetic nephropathy.