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Giant keratogenous cysts are rare and mimic other common benign lesions in the head and neck area. The giant cysts have tendency for malignant change. We report a case of a giant keratogenous cyst in the scalp area of a middle aged female which mimicked lipoma /Plexiform neurofibroma on clinical examination. Complete surgical excision was done, and on histology examination, the final diagnosis of Keratinous cyst was made. The follow-up period of 06 months is normal. Kerarogenous cysts are either congenital or acquired.