Fig. 4. Effects of the compound 5 on the PGE2 (A) and TNF-α productions (B); effects of the compound 18 on the PGE2 (C) and TNF-α productions (D). The cells were stimulated with LPS (1 μg/mL) 2 h and then for treated with the compounds (12.5, 25, 50 μM) for 24 h. PGE2 and TNF-α concentration in the supernatants were measured using ELISA. Dexamethasone was used as positive reference compound at the same concentration with compounds. Values re the mean ± SE of three determinations. ***p <0.001 compared with cells treated by LPS.

Published as part of Huang, Yan, Pan, Liwei, Chang, Yanling, Liang, Xiaoqin, Hou, Ping, Ren, Chenyang, Xu, Weifeng, Yang, Ruiyun, Li, Jun & Liu, Buming, 2023, Megastigmane glycosides from Streblus ilicifolius (S.Vidal) Corner and their anti-inflammatory activity, pp. 1-13 in Phytochemistry (113606) 208 on page 8, DOI: 10.1016/j.phytochem.2023.113606, http://zenodo.org/record/8230388