The present study aimed to assess and compare the levels of calcium in cases and controls with and without seizure disorders respectively. It also aimed to assess association of serum calcium levels with time since seizures and causes of seizures. This case control study conducted in Department of Medicine, People’s Hospital Bhopal for a period of 18 months included 77 cases with seizure disorders and equal number of controls without seizure disorders. Data regarding detailed history regarding presenting complaints, time siThe present study aimed to assess and compare the levels of calcium in cases and controls with and without seizure disorders respectively. It also aimed to assess association of serum calcium levels with time since seizures and causes of seizures. This case control study conducted in Department of Medicine, People’s Hospital Bhopal for a period of 18 months included 77 cases with seizure disorders and equal number of controls without seizure disorders. Data regarding detailed history regarding presenting complaints, time since onset of seizures, causes of seizures was obtained from cases. Mean calcium level amongst cases was 8.99±0.75 mg/dl and that amongst controls was 9.32±1.11 mg/dl. The present study observed significantly lower calcium level amongst cases as compared to controls (p<0.05). No statistically significant association of mean calcium level was observed with time since seizures and various causes of seizures (p>0.05). Serum calcium levels has significant association with seizures since there is some level of hypocalcemia in few though not all seizure patients. Calcium supplementation may be considered in patients with intractable seizures and in patients with drug refractory seizures. Thus calcium levels must be evaluated in every seizure patient irrespective of cause.nce onset of seizures, causes of seizures was obtained from cases. Mean calcium level amongst cases was 8.99±0.75 mg/dl and that amongst controls was 9.32±1.11 mg/dl. The present study observed significantly lower calcium level amongst cases as compared to controls (p<0.05). No statistically significant association of mean calcium level was observed with time since seizures and various causes of seizures (p>0.05). Serum calcium levels has significant association with seizures since there is some level of hypocalcemia in few though not all seizure patients. Calcium supplementation may be considered in patients with intractable seizures and in patients with drug refractory seizures. Thus calcium levels must be evaluated in every seizure patient irrespective of cause.

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