Infectious diseases are continuing threat to all patients, regardless of the age, gender, lifestyle, ethnic background and socioeconomic status. Health care is always facing new danger from incurable infections. Nurses play an important role in the health care team, they need to have current knowledge related to emerging and re-emerging infectious diseases. Student nurses are often exposed to various infections during their clinical experience as a part of curriculum. As a member of health care team, nursing students have huge responsibility to protect themselves, patients and other members of health team. The aim of the study was to impart the knowledge on infection control measures through video assisted programme among nursing students in order to protect themselves and patients in the clinical field. A quasi-experimental study, one group pre- and posttest design, 150 nursing students was conducted in selected nursing college. Pretest was assessed with demographic profile of nursing students and knowledge questionnaire followed by videos was displayed to the participants regarding specific infection control measures of Hand hygiene and personal protective equipment's (PPE). The post test was conducted after 7 days with same tools used in pretest assessment. The level of knowledge on hand washing technique after video assisted teaching programme on infection control measures increased significantly by 50% in the posttest with mean difference of 2.18,t=14.76 ; the level of knowledge on PPE after video assisted teaching programme on infection control measures increased significantly by 57.4% in the posttest with mean difference of 1.02,t=14.42 at 0.05 level of significant. Statistically significant association between the pretest level of knowledge on hand washing with scores of nursing 2 2 2 programme (x = 39.76, p<0.001), year of experience (x = 33.19, p<0.001), year of study (x = 41.35, p<0.001); association 2 between the pretest level of knowledge on PPE with scores of gender (x = 15.50, p<0.001) nursing programme (x = 54.07, 2 2 p<0.001), year of experience (x = 41.65, p<0.001), year of study (x = 70.46, p<0.001) was found. Video-assisted teaching programme was effective to enhance the knowledge of hand washing and use of PPE as infection prevention control measures among nursing students in order to protect themselves and patients their practice field and community.

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