There are several new thyroid hormone preparations that can be used to treat patients with hypothyroidism. These include a new preparation of levothyroxine called Tirosint that is the only thyroid preparation in a gel capsule. There is also new preparation of desiccated thyroid (from porcine thyroid) called WP thyroid, that is similar to Nature-Throid. Many patients have trouble absorbing standard thyroid preparations such as levothyroxine,Synthroid or Levoxyl. Certain conditions and several medications (calcium, iron, vitamins thatcontain calcium and iron, and antacids or proton-pump inhibitors) affect absorption of levothyroxine that can lead to variable thyroid levels with resultant symptoms of either hypothyroidism. Keywords: Levothyroxine TIROSINT