Fig. 3. Effects of compound 5 on 6-OHDA-induced PC12 cell injury. (A) PC12 cells were preincubated with different concentration of compound 5 for 30 min and then exposed to 6-OHDA for 24 h. The values are presented as the mean ±SD (n =3). *p <0.05 versus 6-OHDA group; #p <0.05 versus control group. (B) PC12 cells were treated with different concentration of compound 5 for 24 h. The values are presented as the mean ± SD (n = 3). *p <0.05 versus control group. (C) The changes of morphology of PC12 cells in present of compound 5. (a) Control; (b) 6-OHDA group; (c) 6-OHDA and 5 μM compound 5 treatment; (d) 6-OHDA and 10 μM compound 5 treatment.

Published as part of Zhang, Xia, Chen, Bin, Xie, Yuan, Hu, Yeye, Niu, Zhiqiang, He, Ziliang, Wang, Lun, Zhang, Guolin, Wang, Mingkui, Hu, Weicheng & Li, Fu, 2023, Phenolic compounds from the flowers of Rosa hugonis Hemsl. and their neuroprotective effects, pp. 1-9 in Phytochemistry (113589) 208 on page 5, DOI: 10.1016/j.phytochem.2023.113589, http://zenodo.org/record/8194566