We demonstrate a novel realization of Interstitial fiber, broadband, Time Domain Diffuse Optical Spectroscopy (TD-DOS) in Null Source-Detector separation (NSDS) approach without temporal gating, by using a Superconducting Nanowire single photon detector (SNSPD) for acquisition. As per the MEDPHOT protocol, we test experimentally, the absorption linearity of the system on tissue-equivalent liquid phantoms, and demonstrate the scattering-independent retrieval of the absorption spectrum of water using Intralipid phantoms in the wavelength range of 600-1100 nm. This work has been published in the Journal of Biomedical Optics - https://doi.org/10.1117/1.JBO.28.12.121202. Here, we present the dataset containing the acquired data pertaining to the aforementioned publication, including a brief overview, the tools to read it and the analysis corresponding to the figures in the article.

{"references": ["Vamshi Damagatla, Pranav Lanka, Annalisa Brodu, Niels Noordzij, Jessie Qin-Dregely, Andrea Farina, Antonio Pifferi, \"Interstitial null-distance time-domain diffuse optical spectroscopy using a superconducting nanowire detector,\" J. Biomed. Opt. 28(12) 121202 (3 April 2023) https://doi.org/10.1117/1.JBO.28.12.121202", "Vamshi Damagatla, Pranav Lanka, Andrea Farina, Annalisa Brodu, Niels Noordzijc, Jessie Qin-Dregely, Antonio Pifferi, \"Superconducting nanowire detector for interstitial null-seperation time-domain diffuse optical spectroscopy,\" Proc. SPIE 12376, Optical Tomography and Spectroscopy of Tissue XV, 123760F (7 March 2023); https://doi.org/10.1117/12.2649028"]}