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A recipe for extremely reproducible enrichment analysis (software repository)

Authors: Ziemann, Mark; Bora, Anusuiya;

A recipe for extremely reproducible enrichment analysis (software repository)

Abstract

Computational reproducibility is difficult, especially over longer timeframes. In bioinformatics research, functional enrichment analysis is typically conducted in an irreproducible way. This repository is designed to instruct researchers on how to improve the reproducibility of pathway enrichment analysis. Using a Docker image allows researchers to keep a stable compute environment with a known version of operating system, R and packages. The downside of Docker is that working with it is typically done with the command line, and requires a relatively high degree of specialised knowledge. This work is designed to help researchers make their enrichment analyses more reproducible by providing two important things: Templates for a functional Docker container with R-based enrichment tools. Step-by-step guides to help users customise templates and deploy analyses in their research projects.

Release of GitHub repo https://github.com/markziemann/enrichment_recipe

Related Organizations
Keywords

FOS: Computer and information sciences, Enrichment analysis, Pathway analysis, Bioinformatics, Reproducibility

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selected citations
These citations are derived from selected sources.
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
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