Objective: To evaluate the benefits of percutaneous coronary intervention (PCI) in reducing NT- proBNP levels and increasing left ventricular ejection fraction in elderly patients. Methods: based on the data of the regional branch of the Republican Specialized Cardiology Scientific and Practical Medical Center of the Samarkand region, elderly patients who underwent PCI in the period from September 1 to March 1, 2022 were analyzed. A total of 80 patients were analyzed, in whom interventional intervention (IT) was performed from the radial approach in 58.75% (n=74) and from other approaches in 3.68% (n=6). Men 68.1% (n=43), women 31.9% (n=37). The mean age was 63.46 years. Results. The study showed that in elderly people diagnosed with coronary artery disease, the following were detected: post-infarction cardiosclerosis (PICS) - 40% (n=32), 42.5% (n=34) with myocardial infarction, angina pectoris FS 3 - 17.5% ( n=14). As can be seen from diagram 2, the curved branch is most often damaged, in 40 patients the average damage rate is 80%, damage to the anterior interventricular septum (AVS) - 20 (25%), while the average damage rate is 70%, in 14 patients the damage to the right of the coronary artery (PCA), which is 70% of the average level, in 49 patients the defeat of the peripheral branches (PBV), which is 69%, of the diagonal branches. (DV) was observed in 2 patients and amounted to 78%, in whom stenting of the coronary arteries was performed, the levels of LV EF, E/e' and NTproBNP were significantly increased. Conclusion. Currently, interventional surgery, including coronary artery stenting, balloon angioplasty and coronary artery bypass grafting, is in the first place in the treatment of patients with coronary heart disease. At the same time, a more careful approach should be taken to comorbid patients, taking into account the age of patients with chronic heart failure, for whom it is important to study the level of natriuretic peptide, as well as long-term monitoring of treatment results.