Periodontal regeneration is an old idea that is evolving because to the adoption of more modern and altered barrier membranes to get better clinical results. The placental amnion and chorion membranes are examples of these membranes. Its biocompatibility and capacity to speed up wound healing led to its initial use.As part of guided tissue regeneration and guided bone regeneration, the membrane has been utilised in periodontology to reduce probing pocket depth, raise clinical attachment levels, and encourage bone formation. Since these membranes are biologic, they can be broken down by the body and work with tissue.It has also been utilised to treat intrabony abnormalities, guided bone regeneration, and root covering therapies. The special characteristics of this membrane that make it ideal for periodontal surgery, together with the clinical repercussions and literature evaluation.