The aim of present research work is evaluate antioxidant and antipyretic activity of hydroalcoholic extract of cassia auriculata. Cassia auriculata commonly known as Tanner’s Cassia is an important medicinal shrub used in traditional systems of medicine. Subcutaneous injection of sterilized brewer’s 20 % yeast suspended in 9.0 % in saline at the dose of 1 mL/100 g body weight in albino rat leads to pyrexia. The results conclude that the extract of Cassia auriculata exhibited significant antipyretic activity. While Antioxidant activity of hydroalcoholic extract of Cassia auriculata was used as a conventional compound with ascorbic acid. Free radical hydrogen peroxide scavenging activity (percent) has been calculated. Keywords: Pyrexia, Estimation, Phytoconstituents, Extraction, Percentage yield