This comprehensive review aims to provide an in-depth exploration of the role of psychological factors in the management of low-back pain (LBP). It examines the underlying mechanisms through which psychological factors influence LBP, the impact of psychological interventions on LBP outcomes, and the challenges associated with integrating psychological care into LBP management. The review highlights the importance of adopting a biopsychosocial approach to LBP, which recognizes the complex interplay between biological, psychological, and social factors in shaping the experience and management of LBP. By addressing the psychological dimensions of LBP, healthcare providers can offer more effective and holistic care, ultimately improving treatment outcomes and patient satisfaction.