Patient-specific implant (PSI) is a personalized approach to reconstructive and esthetic surgery. This is particularly useful in maxillofacial surgery as well as prosthodontics, in which restoring the complex three-dimensional (3D) contour can be quite challenging. In certain situations, the best results can only be achieved with implants custom made to fit a particular need. Among the various alloplastic materials, polyether-ether ketone (PEEK) has emerged as an attractive option for the PSI. Significant progress has been made over the past decade in the design and manufacture of maxillofacial PSIs using additive manufacturing (AM) technology. This paper gives a brief review of Patient Specific Implants, its manufacturing, indications and materials used in maxillofacial surgery.