This article presents the comparative analysis of genus and species of Boraginaceae Juss. distributed in Azerbaijan and its neighboring countries (the Dagestan Autonomous Republic (Russian Federation), Georgia, Armenia, Turkey and the Islamic Republic of Iran). In order to compare the similarity of plant species distributed in two neighbor countries the floristic similarity coefficient was determined using the floristic similarity coefficient of Jaccard index. The results of the analysis showed that Borag- inaceae distributed in Azerbaijan has a closer commonness with the flora of Armenia, Georgia and Dagestan for its taxonomic composition, than with the floras of Turkey and Iran. This may be at- tributed to the degree of comparison of the measured areas of the investigated territories, the type of areal or geographic elements that affect the formation of these territories, similarity and differences in climatic conditions.