Changes in Lacrimation in experimentally induced Corneal Ulcers in Rabbits, treated with Third Eyelid Flap, Hyaluronic Acid and Platelet-Rich Plasma products

A clinical study was conducted on the effect of the lacrimation in New Zealand White rabbits (Oryctolagus cuniculus) treated with 4 different therapies (Third Eyelid Flap, hyaluronic acid eye drops, platelet-rich plasma as a single subconjunctival injection and as a triple daily instillation). For the study, daily measurements of tear production were performed using the 1-min Schirmer Tear Test (STT-I). In all groups, increased STT-I values were observed until the 3rd day after ulceration. Hyaluronic acid and platelet-rich plasma decreased the STT-I values to the baseline by the end of the study, with the earliest results noticed with plasma drops. Observed STT-I values in third eyelid fixation by the study's end are higher compared to the untreated eyes in the Control group.

Country

Bulgaria

Related Organizations

National Centre for Information and Documentation
Bulgaria
University of Forestry
Bulgaria

Keywords

corneal ulcer, New Zealand White, http://www.journalresearchijf.com/current-issue/, rabbit, lacrimation, Schirmer Tear Test, STT

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