Central nervous system tuberculosis is a major cause of morbidity and mortality in developing countries. Intracranial tuberculoma is rare and is one of the most serious cases of tuberculosis. We report a case of tuberculous meningoencephalitis complicated by tuberculous abscesses, in a 10-month-old boy with angina and otorrhea 42 days ago. A CT scan of the brain and Rochers TDM showed aggressive bilateral otomastoiditis, more marked on the left, multiple left supratentorial brain formations with subfactorial and temporal involvement in relation to abscesses. Mycobacterium tuberculosis was isolated in the CSF fluid and in the brain pus after surgical drainage. Good clinical and radiological improvement was observed after surgery and treatment with corticosteroids and antituberculosis drugs.