A virtual machine for the benchmark workflow of cell-cell interaction prediction tools for sc-RNA seq data. It contains the seven CCI prediction tools under comparison, scRNA-seq datasets of IPF to be used as input, a manually curated gold standard of known IPF CCIs, a jupyter notebook with the main workflow, and associated functions. The workflow corresponds to the paper "A comparison of cell-cell interaction prediction tools based on scRNA-seq data" (2023) by Zihong Xie, Xuri Li, and Antonio Mora". The password for login is "bio2021".