Artificial Intelligence(AI), Machine Learning(ML) and Big Data are facilitating the present society as front runner beneficiary, This review highlights the imactful use of AI, ML and Big Data in diverse areas of pharmaceutical fields. Drug Discovery and development with collaborative inputs of technology reducing the human workload as achieving the target in a short period. This paper surveys big data with highlighting the big data analytics. Big data analytics covers integration and analysis of large amount of complex heterogeneous data such as various – omics data (genomics, epigenomics, transcriptomics, proteomics, metabolomics, interactomics, pharmacogenomics, diseasomics), biomedical data and electronic health records data. We underline the challenging issues about big data privacy and security. Keywords: Artificial Intelligence(AI), Machine Learning(ML) and Big Data, Technology, Big Data Analytics, Data Mining, Health Informatics, Healthcare Information