In some parts of the world, particularly in Asia, where they are the leading causes of blindness, ocular fungal infections are thought to be a substantial cause of considerable vision loss. The cornea is usually damaged by the inflammatory process, although it can also impact the orbit, eyelids, lacrimal apparatus, conjunctiva, sclera, and interior components of the eye. The diagnosis and treatment of ocular infections with a fungal aetiology continue to be difficult for ophthalmologists. Establishing a clinical diagnosis, isolating the fungus responsible for the infection, and providing effective local treatment, particularly in cases of corneal infections, are the key challenges. Negative predictive factors include insufficient initial treatment and delayed diagnosis brought on by a lack of suspicion of a fungal cause. The poor commercial availability of drug formulations and the poor penetration of antifungal medications into the eye tissue are also problems.