Accurate prediction on clopidogrel's abnormal behaviors and pharmacobehavioral economics

Summary Thirteen years ago, under asymmetric conditions, by analyzing the abnormal economic behavior and game process of clopidogrel after marketing, based on behavioral economics theory, we predicted that there were problems in the results of phase III CAPRIE trial. Three years later, direct evidence was discovered in CAPRIE's Table 6. The vital data of fatal events in many groups, and the nyrs in all subgroups were unbalanced and illogical. The CAPRIE's results were mistaken, and clopidogrel couldn't be superior to aspirin. The wrong data, noise trading, companion effect, herd behavior, and butterfly effect, etc. made clopidogrel's global total sales exceed $90 billion. We proposed modifying guidelines for clopidogrel, medical statistical theory, and constructing new disciplines such as pharmacobehavioral, medical behavioral, health behavioral economics, etc. Although our empirical study revealed negative information, we found that only several drugs caused changes in medical behavior, resulting in economic growth of more than $826.5 billion.[ The latest modified and updated version is: version 7; Li Liu1*, FanDian Zeng2, XiaoYan Yang2. (2022). Accurate prediction on clopidogrel's abnormal behaviors and pharmacobehavioral economics. Zenodo. https://doi.org/10.5281/zenodo.7995680]

The abstract of this paper was presented at the 12th China Medical Genetics conference in April 2013. This paper was presented at two preprint platforms in March 2021 and 2022. Li Liu, FanDian Zeng, & XiaoYan Yang. Zenodo. https://doi.org/10.5281/ zenodo. 5973274.; Liu, Li (2021): Prediction on Clopidogrel's Abnormal Behaviors and Pharmacobehavioral Economics. figshare. Preprint. https://doi.org/10.6084/m9. figshare.14173727. v26.

Related Organizations

Wuhan University of Science and Technology
China (People's Republic of)
Wuhan University
China (People's Republic of)
Huazhong University of Science and Technology
China (People's Republic of)

Keywords

clopidogrel ˑ invisible hand ˑ behavioral economics ˑ game theory justice ˑ morality ·• market failure · clinical behavioral economics · health behavioral economics · prospect theory · pharmacobehavioral economics · medical behavioral economics · post-truth · metrological medical ethics · metrological media ethics · metrological journalism ethics · quantitative economic ethics metrological business ethics · metrological management ethics · quantitative administrative ethics · metrological political ethics · metrological party ethics · quantitative politics · evidence-based medicine · pegfilgrastim · filgrastim · common cold · conscience · prediction · adverse drug reaction · treatment guideline · welfare economics · COVID-19 SARS-CoV-2 · economic recovery · omeprazole · esomeprazole · proton-pump inhibitors · national governance · political behavioral economics · party behavioral economics · government behavioral economics · national behavioral economics · enterprise behavioral economics · rural behavioral economics · agricultural behavioral economics · COVID-19 vaccine · world peace, clopidogrel ˑ invisible hand ˑ behavioral economics ˑ game theory justice ˑ morality ·• market failure · clinical behavioral economics · health behavioral economics · prospect theory · pharmacobehavioral economics · medical behavioral economics · post-truth · metrological medical ethics · metrological media ethics · metrological journalism ethics · quantitative economic ethics metrological business ethics · metrological management ethics · quantitative administrative ethics · metrological political ethics · metrological party ethics · quantitative politics · evidence-based medicine · pegfilgrastim · filgrastim · common cold · conscience · prediction · adverse drug reaction · treatment guideline · welfare economics · COVID-19 SARS-CoV-2 · economic recovery · omeprazole · esomeprazole · proton-pump inhibitors · national governance · political behavioral economics · party behavioral economics · government behavioral economics · national behavioral economics · enterprise behavioral economics · rural behavioral economics · agricultural behavioral economics · COVID-19 vaccine ·medical insurance, clopidogrel ˑ invisible hand ˑ behavioral economics ˑ game theory justice ˑ morality ·• market failure · clinical behavioral economics · health behavioral economics · prospect theory · pharmacobehavioral economics · medical behavioral economics · post-truth · metrological medical ethics · metrological media ethics · metrological journalism ethics · quantitative economic ethics metrological business ethics · metrological management ethics · quantitative administrative ethics · metrological political ethics · metrological party ethics · quantitative politics · evidence-based medicine · pegfilgrastim · filgrastim · common cold · conscience · prediction · adverse drug reaction · treatment guideline · welfare economics · COVID-19 SARS-CoV-2 · economic recovery · omeprazole · esomeprazole · proton-pump inhibitors · national governance · political behavioral economics · party behavioral economics · government behavioral economics · national behavioral economics · enterprise behavioral economics · rural behavioral economics · agricultural behavioral economics · COVID-19 vaccine ·medical insurance, clopidogrel ˑ invisible hand ˑ behavioral economics ˑ game theory justice ˑ morality ·• market failure · clinical behavioral economics · health behavioral economics · prospect theory · pharmacobehavioral economics · medical behavioral economics · post-truth · metrological medical ethics · metrological media ethics · metrological journalism ethics · quantitative economic ethics metrological business ethics · metrological management ethics · quantitative administrative ethics · metrological political ethics · metrological party ethics · quantitative politics · evidence-based medicine · pegfilgrastim · filgrastim · common cold · conscience · prediction · adverse drug reaction · treatment guideline · welfare economics · COVID-19 SARS-CoV-2 · economic recovery · omeprazole · esomeprazole · proton-pump inhibitors · national governance · political behavioral economics · party behavioral economics · government behavioral economics · national behavioral economics · enterprise behavioral economics · rural behavioral economics · agricultural behavioral economics · COVID-19 vaccine · world peace

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