This strategy document prepared by the LIBSENSE Working Group on Infrastructure outlines a roadmap for implementing Persistent Identifiers (PIDs) in Africa. PIDs serve as long-lasting references to digital objects, enhancing the cohesion and discoverability of African scholarly content. Embracing open infrastructure and prioritising PIDs can increase African scholarly outputs, improve visibility and accessibility, and make research data FAIR. The roadmap recommends selecting open, non-commercial, and community-driven PID systems, developing appropriate governance and finance models, establishing national and regional PIDs consortia, and advocating for flexible fee models. It addresses barriers, fosters collaboration, and ensures sustainable implementation and adoption of PIDs in African research and scholarly communication.