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This repository contains all codes used in the paper: "Uncovering the hidden structure of dynamic T cell composition in peripheral blood during cancer immunotherapy: a topic modeling approach". If you find the method useful, please cite: X. Peng, J. Lee, M. Adamow, C. Maher, M. A. Postow, M. Callahan, K. S. Panageas, R. Shen (2023). "Uncovering the hidden structure of dynamic T cell composition in peripheral blood during cancer immunotherapy: a topic modeling approach". [bioRxiv] You can find the tutorial for the method described in the paper here. In v1.0, we added source codes for new figures generated during the revision.
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